Immuno-oncology drugs stimulate the immune-system of the patient to fight cancer cells. These effects might be enhanced by using Pawlowing conditioning of external stimuli to the drug. For example, Pawlow demonstrated that by exposing dogs (cf patients) to the ringing of a bell  (eg white coat of clinician) during feeding time, the unconditioned reaction of … Continue reading Psychoneuroimmunoloy as a missed opportunity in immuno-oncology drug development